› 3vnh

X-ray diffraction
2.1Å resolution

Crystal Structure of Keap1 Soaked with Synthetic Small Molecular

Released:
DOI: 10.2210/pdb3vnh/pdb
PDB entry 3vnh coloured by chain, front view.
PDB entry 3vnh coloured by chain, side view.
PDB entry 3vnh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kunishima N, Tanaka T, Satoh M, Saburi H

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171933 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kelch-like ECH-associated protein 1 Chain: A
Molecule details ›
Chain: A
Length: 309 amino acids
Theoretical weight: 33.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14145 (Residues: 321-609; Coverage: 46%)
Gene names: INRF2, KEAP1, KIAA0132, KLHL19
Sequence domains: Kelch motif
Structure domains: Kelch-type beta propeller

Ligands and Environments

1 bound ligand:
Ligand FUU 1 x FUU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P6522
Unit cell:
a: 85.368Å b: 85.368Å c: 145.903Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.201 0.211
Expression system: Escherichia coli

Quick links