› 3vyi

X-ray diffraction
2.3Å resolution

Crystal Structure of a trimeric coiled-coil (I/I-type) assembly domain from the voltage-gated proton channel mutant

Released:
DOI: 10.2210/pdb3vyi/pdb
PDB entry 3vyi coloured by chain, front view.
PDB entry 3vyi coloured by chain, side view.
PDB entry 3vyi coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Gating of the designed trimeric/tetrameric voltage-gated H+ channel.
Fujiwara Y, Kurokawa T, Takeshita K, Nakagawa A, Larsson HP, Okamura Y
J Physiol 591 627-40 (2013)
PMID: 23165764

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174830 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-gated hydrogen channel 1 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 51 amino acids
Theoretical weight: 5.92 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3U2S8 (Residues: 220-269; Coverage: 19%)
Gene names: Bts, Hvcn1, Vsop
Sequence domains: C-terminal membrane-localisation domain of ion-channel, VCN1
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: P212121
Unit cell:
a: 83.273Å b: 84.01Å c: 88.393Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.232 0.295
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family.
DeCoursey TE. (2013)
7 more