Function and Biology Details
Reaction catalysed:
(1a) ATP + [DNA ligase]-L-lysine = [DNA ligase]-N(6)-(5'-adenylyl)-L-lysine + diphosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Nucleic acid-binding, OB-fold
- DNA ligase, ATP-dependent, conserved site
- DNA ligase, ATP-dependent, central
- DNA ligase, ATP-dependent, N-terminal domain superfamily
- DNA ligase, ATP-dependent, C-terminal
- DNA Ligase 4, adenylation domain
- DNA ligase, ATP-dependent
- DNA ligase, ATP-dependent, N-terminal
1 more domain
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Protein artemis and DNA ligase 4 (preferred)
PDBe Complex ID:
PDB-CPX-156093 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA ligase 4
Molecule details ›
Chain: A
Length: 610 amino acids
Theoretical weight: 69.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 610 amino acids
Theoretical weight: 69.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P49917 (Residues: 1-609; Coverage: 67%)
Sequence domains:
Structure domains:
Protein artemis
