› 3woy

X-ray diffraction
2.1Å resolution

Crystal structure of CLASP2 TOG domain (TOG2)

Released:
DOI: 10.2210/pdb3woy/pdb
PDB entry 3woy coloured by chain, front view.
PDB entry 3woy coloured by chain, side view.
PDB entry 3woy coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics.
Maki T, Grimaldi AD, Fuchigami S, Kaverina I, Hayashi I
J Mol Biol 427 2379-95 (2015)
PMID: 26003921

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130837 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CLIP-associating protein 2 Chain: A
Molecule details ›
Chain: A
Length: 251 amino acids
Theoretical weight: 28.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75122 (Residues: 60-310; Coverage: 19%)
Gene names: CLASP2, KIAA0627
Sequence domains: CLASP N terminal
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A, PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P3221
Unit cell:
a: 58.812Å b: 58.812Å c: 157.073Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.183 0.237
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Nucleation and Dynamics of Golgi-derived Microtubules.
Sanders et al. (2015)
3 more

2 mentions without citation

CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics.
Maki et al. (2015)
1 more