3wpq

X-ray diffraction
1.84Å resolution

crystal structure of the GAP domain of MgcRacGAP(S387A)

Released:
Source organism: Homo sapiens
Entry authors: Murayama K, Kato-Murayama M, Shirouzu M, Kitamura T, Yokoyama S

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-190478 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rac GTPase-activating protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 208 amino acids
Theoretical weight: 23.18 KDa
Source organism: Homo sapiens
Expression system: cell-free protein synthesis
UniProt:
  • Canonical: Q9H0H5 (Residues: 346-546; Coverage: 32%)
Gene names: KIAA1478, MGCRACGAP, RACGAP1
Sequence domains: RhoGAP domain
Structure domains: Rho GTPase activation protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 48.96Å b: 53.61Å c: 86.388Å
α: 90° β: 97.03° γ: 90°
R-values:
R R work R free
0.167 0.167 0.2
Expression system: cell-free protein synthesis