Function and Biology Details
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156533 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-1
Molecule details ›
Chain: A
Length: 461 amino acids
Theoretical weight: 49.87 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 461 amino acids
Theoretical weight: 49.87 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P52293 (Residues: 72-497; Coverage: 81%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Nucleolar RNA helicase 2
Molecule details ›
Chains: B, C
Length: 14 amino acids
Theoretical weight: 1.59 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Length: 14 amino acids
Theoretical weight: 1.59 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q9JIK5 (Residues: 839-851; Coverage: 2%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup:
P212121
Expression system: Escherichia coli BL21(DE3)
