Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
A20p37 (preferred)
PDBe Complex ID:
PDB-CPX-149310 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
A20p50
Molecule details ›
Chain: A
Length: 366 amino acids
Theoretical weight: 43.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: OTU-like cysteine protease
Length: 366 amino acids
Theoretical weight: 43.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P21580 (Residues: 1-366; Coverage: 46%)
Sequence domains: OTU-like cysteine protease
A20p50
Molecule details ›
Chain: B
Length: 366 amino acids
Theoretical weight: 43.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: OTU-like cysteine protease
Length: 366 amino acids
Theoretical weight: 43.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P21580 (Residues: 1-366; Coverage: 46%)
Sequence domains: OTU-like cysteine protease
