› 3apa

X-ray diffraction
1.65Å resolution

Crystal structure of human pancreatic secretory protein ZG16p

Released:
DOI: 10.2210/pdb3apa/pdb
PDB entry 3apa coloured by chain, front view.
PDB entry 3apa coloured by chain, side view.
PDB entry 3apa coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of human secretory proteins ZG16p and ZG16b reveal a Jacalin-related β-prism fold.
Kanagawa M, Satoh T, Ikeda A, Nakano Y, Yagi H, Kato K, Kojima-Aikawa K, Yamaguchi Y
Biochem Biophys Res Commun 404 201-5 (2011)
PMID: 21110947

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130101 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zymogen granule membrane protein 16 Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 15.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60844 (Residues: 21-159; Coverage: 92%)
Gene name: ZG16
Sequence domains: Jacalin-like lectin domain
Structure domains: Jacalin-like lectin domain

Ligands and Environments

2 bound ligands:
Ligand GOL 1 x GOL
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P21212
Unit cell:
a: 58.88Å b: 73.217Å c: 30.096Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.204 0.227
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Recognition of microbial glycans by soluble human lectins.
Wesener et al. (2017)
4 more

11 mentions without citation

Structural insights into Bacillus thuringiensis Cry, Cyt and parasporin toxins.
Xu et al. (2014)
10 more