› 3aps

X-ray diffraction
1.9Å resolution

Crystal structure of Trx4 domain of ERdj5

Released:
DOI: 10.2210/pdb3aps/pdb
PDB entry 3aps coloured by chain, front view.
PDB entry 3aps coloured by chain, side view.
PDB entry 3aps coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5.
Hagiwara M, Maegawa K, Suzuki M, Ushioda R, Araki K, Matsumoto Y, Hoseki J, Nagata K, Inaba K
Mol Cell 41 432-44 (2011)
PMID: 21329881

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190098 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DnaJ homolog subfamily C member 10 Chains: A, B
Molecule details ›
Chains: A, B
Length: 122 amino acids
Theoretical weight: 13.94 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9DC23 (Residues: 668-789; Coverage: 16%)
Gene names: Dnajc10, Erdj5, Jpdi
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: P21
Unit cell:
a: 56.06Å b: 33.419Å c: 68.343Å
α: 90° β: 92.85° γ: 90°
R-values:
R R work R free
0.208 0.206 0.242
Expression system: Escherichia coli

Quick links

Citations

40 review citations

Molecular chaperone functions in protein folding and proteostasis.
Kim et al. (2013)
39 more

5 mentions without citation

Amino-Pyrazoles in Medicinal Chemistry: A Review.
Lusardi et al. (2023)
4 more