› 3au3

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150339 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenomatous polyposis coli protein Chain: A
Molecule details ›
Chain: A
Length: 344 amino acids
Theoretical weight: 38.68 KDa
Source organism: Homo sapiens
Expression system: cell-free protein synthesis
UniProt:
  • Canonical: P25054 (Residues: 396-732; Coverage: 12%)
Gene names: APC, DP2.5
Sequence domains:
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 14 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P61
Unit cell:
a: 114.327Å b: 114.327Å c: 61.821Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.204 0.232
Expression system: cell-free protein synthesis

Quick links

Citations

6 review citations

Can we safely target the WNT pathway?
Kahn M. (2014)
5 more

2 mentions without citation

Domain architecture of BAF250a reveals the ARID and ARM-repeat domains with implication in function and assembly of the BAF remodeling complex.
Sandhya et al. (2018)
1 more