› 3au5

X-ray diffraction
2.55Å resolution

Structure of the human myosin-X MyTH4-FERM cassette

Released:
DOI: 10.2210/pdb3au5/pdb
PDB entry 3au5 coloured by chain, front view.
PDB entry 3au5 coloured by chain, side view.
PDB entry 3au5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain.
Hirano Y, Hatano T, Takahashi A, Toriyama M, Inagaki N, Hakoshima T
EMBO J 30 2734-47 (2011)
PMID: 21642953

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190807 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Unconventional myosin-X Chains: A, B
Molecule details ›
Chains: A, B
Length: 555 amino acids
Theoretical weight: 63.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HD67 (Residues: 1486-2058; Coverage: 27%)
Gene names: KIAA0799, MYO10
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P21
Unit cell:
a: 85.565Å b: 49.313Å c: 158.407Å
α: 90° β: 93.58° γ: 90°
R-values:
R R work R free
0.236 0.236 0.281
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Myosin-X: a MyTH-FERM myosin at the tips of filopodia.
Kerber et al. (2011)
5 more

4 mentions without citation

Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain.
Hirano et al. (2011)
3 more