› 3b4r

X-ray diffraction
3.3Å resolution

Site-2 Protease from Methanocaldococcus jannaschii

Released:
DOI: 10.2210/pdb3b4r/pdb
PDB entry 3b4r coloured by chain, front view.
PDB entry 3b4r coloured by chain, side view.
PDB entry 3b4r coloured by chain, top view.
Source organism: Methanocaldococcus jannaschii
Primary publication:
Structure of a site-2 protease family intramembrane metalloprotease.
Feng L, Yan H, Wu Z, Yan N, Wang Z, Jeffrey PD, Shi Y
Science 318 1608-12 (2007)
PMID: 18063795

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176486 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc metalloprotease MJ0392 Chains: A, B
Molecule details ›
Chains: A, B
Length: 224 amino acids
Theoretical weight: 24.94 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q57837 (Residues: 1-224; Coverage: 66%)
Gene name: MJ0392
Sequence domains: Peptidase family M50

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: R3
Unit cell:
a: 124.42Å b: 124.42Å c: 136.72Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.251 0.318
Expression system: Escherichia coli

Quick links

Citations

42 review citations

Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL.
Brown et al. (2009)
41 more

27 mentions without citation

Influences of membrane mimetic environments on membrane protein structures.
Zhou et al. (2013)
26 more