› 3bqq

X-ray diffraction
2Å resolution

Crystal Structure of Human Saposin D (triclinic)

Released:
DOI: 10.2210/pdb3bqq/pdb
PDB entry 3bqq coloured by chain, front view.
PDB entry 3bqq coloured by chain, side view.
PDB entry 3bqq coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structures of the human ceramide activator protein saposin D.
Popovic K, Privé GG
Acta Crystallogr D Biol Crystallogr 64 589-94 (2008)
PMID: 18453694

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139656 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Saposin-D Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 80 amino acids
Theoretical weight: 8.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07602 (Residues: 405-484; Coverage: 16%)
Gene names: GLBA, PSAP, SAP1
Sequence domains:
Structure domains: Saposin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P1
Unit cell:
a: 40.66Å b: 41.12Å c: 65.45Å
α: 89.9° β: 81.2° γ: 71.4°
R-values:
R R work R free
0.198 0.195 0.242
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Lysosomal degradation of membrane lipids.
Kolter et al. (2010)
1 more

2 mentions without citation

VaProS: a database-integration approach for protein/genome information retrieval.
Gojobori et al. (2016)
1 more