› 3br0

X-ray diffraction
2.42Å resolution

Crystal Structure of the Complex of Malachite Green Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor

Released:
DOI: 10.2210/pdb3br0/pdb
PDB entry 3br0 coloured by chain, front view.
PDB entry 3br0 coloured by chain, side view.
PDB entry 3br0 coloured by chain, top view.
Source organism: Staphylococcus aureus
Entry author: Brooks BE

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-140955 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator QacR Chains: A, B
Molecule details ›
Chains: A, B
Length: 194 amino acids
Theoretical weight: 22.94 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A0N3 (Residues: 1-188; Coverage: 100%)
Gene names: SAVP031, qacR
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand SO4 12 x SO4
Ligand MGR 1 x MGR
Ligand IMD 2 x IMD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P62
Unit cell:
a: 104.157Å b: 104.157Å c: 97.982Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.214 0.261
Expression system: Escherichia coli

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