› 3bxl

X-ray diffraction
2.3Å resolution

Crystal structure of the R-type calcium channeL (CaV2.3) IQ domain and CA2+calmodulin complex

Released:
DOI: 10.2210/pdb3bxl/pdb
PDB entry 3bxl coloured by chain, front view.
PDB entry 3bxl coloured by chain, side view.
PDB entry 3bxl coloured by chain, top view.
Source organisms:
Entry authors: Mori MX, Vander Kooi CW, Leahy DJ, Yue DT

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-144031 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP29 (Residues: 2-149; Coverage: 99%)
Gene names: CaMI, Calm, Calm1, Cam, Cam1
Sequence domains: EF-hand domain pair
Voltage-dependent R-type calcium channel subunit alpha-1E Chain: B
Molecule details ›
Chain: B
Length: 21 amino acids
Theoretical weight: 2.63 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q15878 (Residues: 1867-1887; Coverage: 1%)
Gene names: CACH6, CACNA1E, CACNL1A6

Ligands and Environments

2 bound ligands:
Ligand CA 4 x CA
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: I4122
Unit cell:
a: 124.606Å b: 124.606Å c: 74.024Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.205 0.262
Expression systems:
  • Escherichia coli
  • Not provided

Quick links