› 3byi

X-ray diffraction
2.25Å resolution

Crystal structure of human Rho GTPase activating protein 15 (ARHGAP15)

Released:
DOI: 10.2210/pdb3byi/pdb
PDB entry 3byi coloured by chain, front view.
PDB entry 3byi coloured by chain, side view.
PDB entry 3byi coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Shrestha L, Tickle J, Elkins J, Burgess-Brown N, Johansson C, Papagrigoriou E, Kavanagh K, Pike ACW, Ugochukwu E, Uppenberg J, von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Doyle D, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-176112 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho GTPase-activating protein 15 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 214 amino acids
Theoretical weight: 24.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q53QZ3 (Residues: 262-473; Coverage: 45%)
Gene names: ARHGAP15, BM-024, BM-030, BM-046
Sequence domains: RhoGAP domain
Structure domains: Rho GTPase activation protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 120.618Å b: 130.142Å c: 62.477Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.188 0.244
Expression system: Escherichia coli

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