› 3cap

X-ray diffraction
2.9Å resolution

Crystal Structure of Native Opsin: the G Protein-Coupled Receptor Rhodopsin in its Ligand-free State

Released:
DOI: 10.2210/pdb3cap/pdb
PDB entry 3cap coloured by chain, front view.
PDB entry 3cap coloured by chain, side view.
PDB entry 3cap coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure of the ligand-free G-protein-coupled receptor opsin.
Park JH, Scheerer P, Hofmann KP, Choe HW, Ernst OP
Nature 454 183-7 (2008)
PMID: 18563085

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136077 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Rhodopsin Chains: A, B
Molecule details ›
Chains: A, B
Length: 348 amino acids
Theoretical weight: 39.03 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02699 (Residues: 1-348; Coverage: 100%)
Gene name: RHO
Sequence domains:
Structure domains: Rhodopsin 7-helix transmembrane proteins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand BGL 6 x BGL
Ligand PLM 2 x PLM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: R3
Unit cell:
a: 242.917Å b: 242.918Å c: 110.42Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.229 0.266

Quick links

Citations

123 review citations

The structure and function of G-protein-coupled receptors.
Rosenbaum et al. (2009)
122 more

117 mentions without citation

Structure-function of the G protein-coupled receptor superfamily.
Katritch et al. (2013)
116 more