› 3cin

X-ray diffraction
1.7Å resolution

CRYSTAL STRUCTURE OF A MYO-INOSITOL-1-PHOSPHATE SYNTHASE-RELATED PROTEIN (TM_1419) FROM THERMOTOGA MARITIMA MSB8 AT 1.70 A RESOLUTION

Released:
DOI: 10.2210/pdb3cin/pdb
PDB entry 3cin coloured by chain, front view.
PDB entry 3cin coloured by chain, side view.
PDB entry 3cin coloured by chain, top view.
Source organism: Thermotoga maritima MSB8
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194787 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myo-inositol-1-phosphate synthase GAPDH-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 394 amino acids
Theoretical weight: 43.71 KDa
Source organism: Thermotoga maritima MSB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X1D6 (Residues: 1-382; Coverage: 100%)
Gene name: TM_1419
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 1 x NAD
2 bound ligands:
Ligand CL 3 x CL
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: I222
Unit cell:
a: 69.304Å b: 104.95Å c: 117.013Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.16 0.194
Expression system: Escherichia coli

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