› 3cqc

X-ray diffraction
2.53Å resolution

Nucleoporin Nup107/Nup133 interaction complex

Released:
DOI: 10.2210/pdb3cqc/pdb
PDB entry 3cqc coloured by chain, front view.
PDB entry 3cqc coloured by chain, side view.
PDB entry 3cqc coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional studies of Nup107/Nup133 interaction and its implications for the architecture of the nuclear pore complex.
Boehmer T, Jeudy S, Berke IC, Schwartz TU
Mol Cell 30 721-31 (2008)
PMID: 18570875

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157619 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear pore complex protein Nup107 Chain: A
Molecule details ›
Chain: A
Length: 270 amino acids
Theoretical weight: 31.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P57740 (Residues: 658-925; Coverage: 29%)
Gene name: NUP107
Sequence domains: Nuclear pore protein 84 / 107
Structure domains: Delta-Endotoxin; domain 1
Nuclear pore complex protein Nup133 Chain: B
Molecule details ›
Chain: B
Length: 227 amino acids
Theoretical weight: 26.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WUM0 (Residues: 935-1156; Coverage: 19%)
Gene name: NUP133
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 51.744Å b: 127.936Å c: 152.738Å
α: 90° β: 97.36° γ: 90°
R-values:
R R work R free
0.218 0.217 0.246
Expression system: Escherichia coli

Quick links

Citations

20 review citations

The structure of the nuclear pore complex.
Hoelz et al. (2011)
19 more

12 mentions without citation

Structural evidence for common ancestry of the nuclear pore complex and vesicle coats.
Brohawn et al. (2008)
11 more