› 3crd

Solution NMR

NMR STRUCTURE OF THE RAIDD CARD DOMAIN, 15 STRUCTURES

Released:
DOI: 10.2210/pdb3crd/pdb
PDB entry 3crd coloured by chain, ensemble of 15 models, front view.
PDB entry 3crd coloured by chain, ensemble of 15 models, side view.
PDB entry 3crd coloured by chain, ensemble of 15 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment.
Chou JJ, Matsuo H, Duan H, Wagner G
Cell 94 171-80 (1998)
PMID: 9695946

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160287 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death domain-containing protein CRADD Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 11.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P78560 (Residues: 1-100; Coverage: 50%)
Gene names: CRADD, RAIDD
Sequence domains: Caspase recruitment domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli

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Citations

53 review citations

Mammalian caspases: structure, activation, substrates, and functions during apoptosis.
Earnshaw et al. (1999)
52 more

13 mentions without citation

Assembly of platforms for signal transduction in the new era: dimerization, helical filament assembly, and beyond.
Ha et al. (2020)
12 more