› 3cx2

X-ray diffraction
1.3Å resolution

Crystal structure of the C1 domain of cardiac isoform of myosin binding protein-C at 1.3A

Released:
DOI: 10.2210/pdb3cx2/pdb
PDB entry 3cx2 coloured by chain, front view.
PDB entry 3cx2 coloured by chain, side view.
PDB entry 3cx2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
An investigation into the protonation states of the C1 domain of cardiac myosin-binding protein C.
Fisher SJ, Helliwell JR, Khurshid S, Govada L, Redwood C, Squire JM, Chayen NE
Acta Crystallogr D Biol Crystallogr 64 658-64 (2008)
PMID: 18560154

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172117 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myosin-binding protein C, cardiac-type Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14896 (Residues: 151-258; Coverage: 9%)
Gene name: MYBPC3
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX10.1
Spacegroup: I41
Unit cell:
a: 48.848Å b: 48.848Å c: 95.132Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 not available 0.209
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Thick Filament Protein Network, Functions, and Disease Association.
Wang et al. (2018)
4 more

7 mentions without citation

Cardiolipin-dependent formation of mitochondrial respiratory supercomplexes.
Mileykovskaya et al. (2014)
6 more