› 3d5f

X-ray diffraction
2.2Å resolution

Crystal Structure of PPAR-delta complex

Released:
DOI: 10.2210/pdb3d5f/pdb
PDB entry 3d5f coloured by chain, front view.
PDB entry 3d5f coloured by chain, side view.
PDB entry 3d5f coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Amano Y

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169863 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisome proliferator-activated receptor delta Chains: A, B
Molecule details ›
Chains: A, B
Length: 267 amino acids
Theoretical weight: 30.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q03181 (Residues: 175-441; Coverage: 61%)
Gene names: NR1C2, PPARB, PPARD
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:
Ligand L41 2 x L41
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32B2
Spacegroup: P21
Unit cell:
a: 39.456Å b: 92.829Å c: 96.454Å
α: 90° β: 98.02° γ: 90°
R-values:
R R work R free
0.278 0.278 0.281
Expression system: Escherichia coli BL21(DE3)

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