› 3dc6

X-ray diffraction
1.8Å resolution

Crystal Structure of a manganese superoxide dismutases from Caenorhabditis elegans

Released:
DOI: 10.2210/pdb3dc6/pdb
PDB entry 3dc6 coloured by chain, front view.
PDB entry 3dc6 coloured by chain, side view.
PDB entry 3dc6 coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans.
Trinh CH, Hunter T, Stewart EE, Phillips SE, Hunter GJ
Acta Crystallogr Sect F Struct Biol Cryst Commun 64 1110-4 (2008)
PMID: 19052361

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151919 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Mn] 1, mitochondrial Chains: A, C
Molecule details ›
Chains: A, C
Length: 198 amino acids
Theoretical weight: 22.14 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: P31161 (Residues: 25-221; Coverage: 89%)
Gene names: F10D11.1, sdm-1, sod-2
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand MN 2 x MN
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P41212
Unit cell:
a: 80.98Å b: 80.98Å c: 137.444Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.201
Expression system: Escherichia coli

Quick links

Citations

6 citation in other articles

Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage.
Cabreiro et al. (2011)
5 more

5 mentions without citation

Centering, scaling, and transformations: improving the biological information content of metabolomics data.
van den Berg et al. (2006)
4 more