› 3dd4

X-ray diffraction
3Å resolution

Structural Basis of KChIP4a Modulation of Kv4.3 Slow Inactivation

Released:
DOI: 10.2210/pdb3dd4/pdb
PDB entry 3dd4 coloured by chain, front view.
PDB entry 3dd4 coloured by chain, side view.
PDB entry 3dd4 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Insights into KChIP4a Modulation of Kv4.3 Inactivation.
Liang P, Wang H, Chen H, Cui Y, Gu L, Chai J, Wang K
J Biol Chem 284 4960-7 (2009)
PMID: 19109250

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-180161 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kv channel-interacting protein 4 Chain: A
Molecule details ›
Chain: A
Length: 229 amino acids
Theoretical weight: 26.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PHZ8 (Residues: 52-250; Coverage: 80%)
Gene names: Calp, Kchip4, Kcnip4
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: I41
Unit cell:
a: 96.3Å b: 96.3Å c: 71.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.239 0.239 0.299
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunits.
Jerng et al. (2014)
2 more

6 mentions without citation

Understanding the physiological roles of the neuronal calcium sensor proteins.
Burgoyne et al. (2012)
5 more