› 3dmw

X-ray diffraction
2.3Å resolution

Crystal structure of human type III collagen G982-G1023 containing C-terminal cystine knot

Released:
DOI: 10.2210/pdb3dmw/pdb
PDB entry 3dmw coloured by chain, front view.
PDB entry 3dmw coloured by chain, side view.
PDB entry 3dmw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human type III collagen Gly991-Gly1032 cystine knot-containing peptide shows both 7/2 and 10/3 triple helical symmetries.
Boudko SP, Engel J, Okuyama K, Mizuno K, Bächinger HP, Schumacher MA
J Biol Chem 283 32580-9 (2008)
PMID: 18805790

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135859 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen alpha-1(III) chain Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 42 amino acids
Theoretical weight: 3.97 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02461 (Residues: 1158-1199; Coverage: 3%)
Gene name: COL3A1
Sequence domains: Collagen triple helix repeat (20 copies)

Ligands and Environments

No bound ligands
2 modified residues:
Ligand HYP 21 x HYP
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 31.98Å b: 21.52Å c: 68.97Å
α: 90° β: 92.58° γ: 90°
R-values:
R R work R free
0.254 0.248 0.274
Expression system: Not provided

Quick links

Citations

9 review citations

Collagen structure and stability.
Shoulders et al. (2009)
8 more

5 mentions without citation

Designing collagens to shed light on the multi-scale structure-function mapping of matrix disorders.
Gahlawat et al. (2024)
4 more