Function and Biology Details
Reactions catalysed:
Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2)
Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
- Transketolase-like, pyrimidine-binding domain
- Thiamin diphosphate-binding fold
- Peripheral subunit-binding domain
- E3-binding domain superfamily
- Biotin/lipoyl attachment
- Transketolase, C-terminal domain
- Dehydrogenase, E1 component
5 more domains
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-146012 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):