3dvm

X-ray diffraction
2.6Å resolution

Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-143918 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 2-149; Coverage: 99%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
Voltage-dependent P/Q-type calcium channel subunit alpha-1A Chain: B
Molecule details ›
Chain: B
Length: 22 amino acids
Theoretical weight: 2.69 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P27884 (Residues: 1963-1982; Coverage: 1%)
Gene names: CACH4, CACN3, CACNA1A, CACNL1A4

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P6122
Unit cell:
a: 43.956Å b: 43.956Å c: 337.87Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.278 0.276 0.32
Expression system: Escherichia coli