› 3dxf

X-ray diffraction
2.2Å resolution

Crystal structure of the HSCARG R37A mutant

Released:
DOI: 10.2210/pdb3dxf/pdb
PDB entry 3dxf coloured by chain, front view.
PDB entry 3dxf coloured by chain, side view.
PDB entry 3dxf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
NADPH is an allosteric regulator of HSCARG.
Dai X, Li Y, Meng G, Yao S, Zhao Y, Yu Q, Zhang J, Luo M, Zheng X
J Mol Biol 387 1277-85 (2009)
PMID: 19254724

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190757 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NmrA-like family domain-containing protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 299 amino acids
Theoretical weight: 33.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HBL8 (Residues: 1-299; Coverage: 100%)
Gene names: HSCARG, NMRAL1
Sequence domains: NmrA-like family
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P21
Unit cell:
a: 46.45Å b: 88.09Å c: 80.201Å
α: 90° β: 89.69° γ: 90°
R-values:
R R work R free
0.244 0.242 0.282
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The phosphate makes a difference: cellular functions of NADP.
Agledal et al. (2010)
4 more