› 3e0c

X-ray diffraction
2.41Å resolution

Crystal Structure of DNA Damage-Binding protein 1(DDB1)

Released:
DOI: 10.2210/pdb3e0c/pdb
PDB entry 3e0c coloured by chain, front view.
PDB entry 3e0c coloured by chain, side view.
PDB entry 3e0c coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure and function of WD40 domain proteins.
Xu C, Min J
Protein Cell 2 202-14 (2011)
PMID: 21468892

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172469 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA damage-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 1140 amino acids
Theoretical weight: 127.1 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: Q16531 (Residues: 1-1140; Coverage: 100%)
Gene names: DDB1, XAP1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 62.607Å b: 124.153Å c: 167.822Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.224 0.283
Expression system: unidentified baculovirus

Quick links

Citations

54 review citations

ATAC-king the complexity of SAGA during evolution.
Spedale et al. (2012)
53 more

7 mentions without citation

The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Wu et al. (2016)
6 more