› 3e3r

X-ray diffraction
2.65Å resolution

Crystal structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family

Released:
DOI: 10.2210/pdb3e3r/pdb
PDB entry 3e3r coloured by chain, front view.
PDB entry 3e3r coloured by chain, side view.
PDB entry 3e3r coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal-structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family.
Dong H, Li X, Lou Z, Xu X, Su D, Zhou X, Zhou W, Bartlam M, Rao Z
J Mol Biol 383 455-64 (2008)
PMID: 18775726

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171838 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcyphosin Chains: A, B
Molecule details ›
Chains: A, B
Length: 204 amino acids
Theoretical weight: 22.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13938 (Residues: 87-275; Coverage: 69%)
Gene name: CAPS
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 9 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P21212
Unit cell:
a: 70.593Å b: 130.411Å c: 46.199Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.228 0.277
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Calcium-regulated mitochondrial ATP-Mg/Pi carriers evolved from a fusion of an EF-hand regulatory domain with a mitochondrial ADP/ATP carrier-like domain.
Harborne et al. (2018)
1 more

5 mentions without citation

Two Essential Light Chains Regulate the MyoA Lever Arm To Promote Toxoplasma Gliding Motility.
Williams et al. (2015)
4 more