› 3e6j

X-ray diffraction
1.67Å resolution

Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 in Complex with H-trisaccharide

Released:
DOI: 10.2210/pdb3e6j/pdb
PDB entry 3e6j coloured by chain, front view.
PDB entry 3e6j coloured by chain, side view.
PDB entry 3e6j coloured by chain, top view.
Source organism: Petromyzon marinus
Primary publication:
Antigen recognition by variable lymphocyte receptors.
Han BW, Herrin BR, Cooper MD, Wilson IA
Science 321 1834-7 (2008)
PMID: 18818359

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174101 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
LRRNT domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 229 amino acids
Theoretical weight: 25.22 KDa
Source organism: Petromyzon marinus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q2VGE8 (Residues: 1-74, 75-194; Coverage: 100%)
Gene name: VLR
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, GAL, FUC
Carbohydrate polymer
2 bound ligands:
Ligand SO4 5 x SO4
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 54.221Å b: 48.564Å c: 55.477Å
α: 90° β: 116.51° γ: 90°
R-values:
R R work R free
0.148 0.146 0.182
Expression system: Spodoptera frugiperda

Quick links

Citations

32 review citations

Origin and evolution of the adaptive immune system: genetic events and selective pressures.
Flajnik et al. (2010)
31 more

12 mentions without citation

VLR-based adaptive immunity.
Boehm et al. (2012)
11 more