› 3edv

X-ray diffraction
1.95Å resolution

Crystal Structure of Repeats 14-16 of Beta2-Spectrin

Released:
DOI: 10.2210/pdb3edv/pdb
PDB entry 3edv coloured by chain, front view.
PDB entry 3edv coloured by chain, side view.
PDB entry 3edv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Localization and structure of the ankyrin-binding site on beta2-spectrin.
Davis L, Abdi K, Machius M, Brautigam C, Tomchick DR, Bennett V, Michaely P
J Biol Chem 284 6982-7 (2009)
PMID: 19098307

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169513 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spectrin beta chain, non-erythrocytic 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 323 amino acids
Theoretical weight: 37.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q01082 (Residues: 1697-2015; Coverage: 14%)
Gene names: SPTB2, SPTBN1
Sequence domains: Spectrin repeat
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments

1 bound ligand:
Ligand MG 13 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 51.335Å b: 56.415Å c: 261.611Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.192 0.25
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Membrane domains based on ankyrin and spectrin associated with cell-cell interactions.
Bennett et al. (2009)
10 more

15 mentions without citation

Localization and structure of the ankyrin-binding site on beta2-spectrin.
Davis et al. (2009)
14 more