› 3elx

X-ray diffraction
1.6Å resolution

Crystal structure of apo Zebrafish Ileal Bile Acid-Binding Protein

Released:
DOI: 10.2210/pdb3elx/pdb
PDB entry 3elx coloured by chain, front view.
PDB entry 3elx coloured by chain, side view.
PDB entry 3elx coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
The X-ray structure of zebrafish (Danio rerio) ileal bile acid-binding protein reveals the presence of binding sites on the surface of the protein molecule.
Capaldi S, Saccomani G, Fessas D, Signorelli M, Perduca M, Monaco HL
J Mol Biol 385 99-116 (2009)
PMID: 18952094

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179762 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gastrotropin Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.19 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6IMW5 (Residues: 2-131; Coverage: 99%)
Gene names: fabp6, zgc:92421
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P3121
Unit cell:
a: 54.422Å b: 54.422Å c: 82.696Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.202 0.24
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Intestinal transport and metabolism of bile acids.
Dawson et al. (2015)
6 more

3 mentions without citation

Structural and Dynamic Determinants of Molecular Recognition in Bile Acid-Binding Proteins.
Toke O. (2022)
2 more