Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Bacterial DNA polymerase III, alpha subunit, NTPase domain
- Nucleic acid-binding, OB-fold
- DNA polymerase III, alpha subunit, PolC-type, Gram-positive bacteria
- DNA polymerase, helix-hairpin-helix motif
- DNA polymerase III alpha subunit finger domain
- PolC, middle finger subdomain superfamily
- PHP domain
- Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC
2 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
DNA polymerase III PolC-type and DNA (preferred)
PDBe Complex ID:
PDB-CPX-116236 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (3 distinct):
DNA polymerase III PolC-type
Molecule details ›
Chain: A
Length: 1041 amino acids
Theoretical weight: 117.25 KDa
Source organism: Geobacillus kaustophilus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 1041 amino acids
Theoretical weight: 117.25 KDa
Source organism: Geobacillus kaustophilus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q5L0J3 (Residues: 228-424, 618-1444; Coverage: 71%)
Sequence domains:
- OB-fold nucleic acid binding domain
- PHP domain
- Bacterial DNA polymerase III alpha NTPase domain
- Bacterial DNA polymerase III alpha subunit finger domain
- Helix-hairpin-helix motif
