› 3fdr

X-ray diffraction
1.75Å resolution

Crystal structure of TDRD2

Released:
DOI: 10.2210/pdb3fdr/pdb
PDB entry 3fdr coloured by chain, front view.
PDB entry 3fdr coloured by chain, side view.
PDB entry 3fdr coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi.
Chen C, Jin J, James DA, Adams-Cioaba MA, Park JG, Guo Y, Tenaglia E, Xu C, Gish G, Min J, Pawson T
Proc Natl Acad Sci U S A 106 20336-41 (2009)
PMID: 19918066

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tudor and KH domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 10.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y2W6 (Residues: 327-420; Coverage: 17%)
Gene names: TDRD2, TDRKH
Sequence domains: Tudor domain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: P212121
Unit cell:
a: 41.565Å b: 45.106Å c: 46.561Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.257
Expression system: Escherichia coli

Quick links

Citations

42 review citations

Establishing, maintaining and modifying DNA methylation patterns in plants and animals.
Law et al. (2010)
41 more

4 mentions without citation

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi.
Chen et al. (2009)
3 more