Function and Biology Details
Reaction catalysed:
4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Ribosomal RNA adenine methyltransferase KsgA/Erm
- Ribosomal RNA adenine dimethylase
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- rRNA adenine dimethylase-like, C-terminal
- Ribosomal RNA adenine methylase transferase, conserved site
- Ribosomal RNA adenine methylase transferase, N-terminal
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Ribosomal RNA small subunit methyltransferase A (preferred)
PDBe Complex ID:
PDB-CPX-130530 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosomal RNA small subunit methyltransferase A
Molecule details ›
Chain: A
Length: 249 amino acids
Theoretical weight: 28.48 KDa
Source organism: Aquifex aeolicus VF5
Expression system: Escherichia coli
UniProt:
Sequence domains: Ribosomal RNA adenine dimethylase
Structure domains:
Length: 249 amino acids
Theoretical weight: 28.48 KDa
Source organism: Aquifex aeolicus VF5
Expression system: Escherichia coli
UniProt:
- Canonical:
O67680 (Residues: 1-248; Coverage: 100%)
Sequence domains: Ribosomal RNA adenine dimethylase
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 22-BM
Spacegroup:
P212121
Expression system: Escherichia coli
