› 3fvc

X-ray diffraction
3.2Å resolution

Crystal structure of a trimeric variant of the Epstein-Barr virus glycoprotein B

Released:
DOI: 10.2210/pdb3fvc/pdb
PDB entry 3fvc coloured by chain, front view.
PDB entry 3fvc coloured by chain, side view.
PDB entry 3fvc coloured by chain, top view.
Source organism: Human herpesvirus 4 strain B95-8
Primary publication:
Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B.
Backovic M, Longnecker R, Jardetzky TS
Proc Natl Acad Sci U S A 106 2880-5 (2009)
PMID: 19196955

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136642 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein B Chain: A
Molecule details ›
Chain: A
Length: 663 amino acids
Theoretical weight: 74.6 KDa
Source organism: Human herpesvirus 4 strain B95-8
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P03188 (Residues: 23-685; Coverage: 79%)
Gene names: BALF4, gB
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 5ID-B
Spacegroup: P321
Unit cell:
a: 106.8Å b: 106.8Å c: 210.75Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.246 0.242 0.283
Expression system: Trichoplusia ni

Quick links

Citations

29 review citations

Fusion of Enveloped Viruses in Endosomes.
White et al. (2016)
28 more

20 mentions without citation

Fusing structure and function: a structural view of the herpesvirus entry machinery.
Connolly et al. (2011)
19 more