› 3g39

X-ray diffraction
1.55Å resolution

Structure of a lamprey variable lymphocyte receptor

Released:
DOI: 10.2210/pdb3g39/pdb
PDB entry 3g39 coloured by chain, front view.
PDB entry 3g39 coloured by chain, side view.
PDB entry 3g39 coloured by chain, top view.
Source organism: Petromyzon marinus
Primary publication:
Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Velikovsky CA, Deng L, Tasumi S, Iyer LM, Kerzic MC, Aravind L, Pancer Z, Mariuzza RA
Nat Struct Mol Biol 16 725-30 (2009)
PMID: 19543291

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112196 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LRRNT domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 170 amino acids
Theoretical weight: 18.49 KDa
Source organism: Petromyzon marinus
Expression system: Escherichia coli
UniProt:
  • Canonical: D0VX17 (Residues: 1-170; Coverage: 100%)
Gene name: vlr
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P65
Unit cell:
a: 49.543Å b: 49.543Å c: 97.912Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.165 0.163 0.199
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Origin and evolution of the adaptive immune system: genetic events and selective pressures.
Flajnik et al. (2010)
17 more

1 mention without citation

Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Velikovsky et al. (2009)