3g6a

X-ray diffraction
2.1Å resolution

Crystal structure of anti-IL-13 antibody CNTO607

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213258 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CNTO607 Fab Light chain Chains: A, L
Molecule details ›
Chains: A, L
Length: 213 amino acids
Theoretical weight: 22.62 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
CNTO607 Fab Heavy chain Chains: B, H
Molecule details ›
Chains: B, H
Length: 229 amino acids
Theoretical weight: 24.46 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P42
Unit cell:
a: 108.05Å b: 108.05Å c: 78.56Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.208 0.283
Expression system: Homo sapiens