› 3g8l

X-ray diffraction
2.5Å resolution

Crystal structure of murine natural killer cell receptor, Ly49L4

Released:
DOI: 10.2210/pdb3g8l/pdb
PDB entry 3g8l coloured by chain, front view.
PDB entry 3g8l coloured by chain, side view.
PDB entry 3g8l coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis.
Back J, Malchiodi EL, Cho S, Scarpellino L, Schneider P, Kerzic MC, Mariuzza RA, Held W
Immunity 31 598-608 (2009)
PMID: 19818651

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191612 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-type lectin domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 190 amino acids
Theoretical weight: 22.07 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JIP9 (Residues: 79-265; Coverage: 71%)
Gene name: Klra12
Sequence domains:
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P3112
Unit cell:
a: 78.045Å b: 78.045Å c: 216.738Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.223 0.287
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Natural killer cell education and tolerance.
Orr et al. (2010)
9 more

4 mentions without citation

Structural basis for recognition of cellular and viral ligands by NK cell receptors.
Li et al. (2014)
3 more