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SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE

Source organism: Mus musculus
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00018
Domain description: SH3 domain
Occurring in:
  1. Growth factor receptor-bound protein 2
The deposited structure of PDB entry 3gbq contains 1 copy of Pfam domain PF00018 (SH3 domain) in Growth factor receptor-bound protein 2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001452
Domain description: SH3 domain
Occurring in:
  1. Growth factor receptor-bound protein 2
IPR036028
Domain description: SH3-like domain superfamily
Occurring in:
  1. Growth factor receptor-bound protein 2
IPR035641
Domain description: GRB2, N-terminal SH3 domain
Occurring in:
  1. Growth factor receptor-bound protein 2
IPR043539
Domain description: Grb2-like
Occurring in:
  1. Growth factor receptor-bound protein 2

Structure domain

CATH CATH domain
2.30.30.40
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 Domains
Occurring in:
  1. Growth factor receptor-bound protein 2
The deposited structure of PDB entry 3gbq contains 1 copy of CATH domain 2.30.30.40 (SH3 type barrels.) in Growth factor receptor-bound protein 2. Showing 1 copy in chain A.
SCOP SCOP annotation
50045
Class: All beta proteins
Fold: SH3-like barrel
Superfamily: SH3-domain
Occurring in:
  1. Growth factor receptor-bound protein 2
The deposited structure of PDB entry 3gbq contains 1 copy of SCOP domain 50045 (SH3-domain) in Growth factor receptor-bound protein 2. Showing 1 copy in chain A.

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