› 3geb

X-ray diffraction
2.4Å resolution

Crystal Structure of edeya2

Released:
DOI: 10.2210/pdb3geb/pdb
PDB entry 3geb coloured by chain, front view.
PDB entry 3geb coloured by chain, side view.
PDB entry 3geb coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Kim SJ

Function and Biology Details

Reaction catalysed: 
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126128 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eyes absent homolog 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 274 amino acids
Theoretical weight: 31.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00167 (Residues: 268-538; Coverage: 50%)
Gene names: EAB1, EYA2
Sequence domains: haloacid dehalogenase-like hydrolase
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand MG 4 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: I4
Unit cell:
a: 183.612Å b: 183.612Å c: 120.15Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.171 0.218
Expression system: Escherichia coli

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