› 3gge

X-ray diffraction
2.6Å resolution

Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2

Released:
DOI: 10.2210/pdb3gge/pdb
PDB entry 3gge coloured by chain, front view.
PDB entry 3gge coloured by chain, side view.
PDB entry 3gge coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Chaikuad A, Hozjan V, Yue W, Cooper C, Elkins J, Pike ACW, Roos AK, Filippakopoulos P, von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
homo hexamer
Assembly name:
PDBe Complex ID:
PDB-CPX-186266 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PDZ domain-containing protein GIPC2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 95 amino acids
Theoretical weight: 10.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TF65 (Residues: 112-200; Coverage: 28%)
Gene name: GIPC2
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

2 bound ligands:
Ligand SO4 2 x SO4
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P4122
Unit cell:
a: 83.51Å b: 83.51Å c: 160.31Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.223 0.265
Expression system: Escherichia coli

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