› 3hxs

X-ray diffraction
2Å resolution

Crystal Structure of Bacteroides fragilis TrxP

Released:
DOI: 10.2210/pdb3hxs/pdb
PDB entry 3hxs coloured by chain, front view.
PDB entry 3hxs coloured by chain, side view.
PDB entry 3hxs coloured by chain, top view.
Source organism: Bacteroides fragilis
Primary publication:
In vivo oxidative protein folding can be facilitated by oxidation-reduction cycling.
Shouldice SR, Cho SH, Boyd D, Heras B, Eser M, Beckwith J, Riggs P, Martin JL, Berkmen M
Mol Microbiol 75 13-28 (2010)
PMID: 19968787

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179165 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 141 amino acids
Theoretical weight: 15.99 KDa
Source organism: Bacteroides fragilis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q64SV7 (Residues: 21-161; Coverage: 99%)
Gene name: BF2672
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P41212
Unit cell:
a: 94.568Å b: 94.568Å c: 82.518Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.196 0.237
Expression system: Escherichia coli

Quick links

Citations

12 review citations

How proteins form disulfide bonds.
Depuydt et al. (2011)
11 more

1 mention without citation

Linking in domain-swapped protein dimers.
Baiesi et al. (2016)