3i00

X-ray diffraction
2.3Å resolution

Crystal Structure of the huntingtin interacting protein 1 coiled coil domain

Released:
Source organism: Homo sapiens
Primary publication:
Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain.
Acta Crystallogr. D Biol. Crystallogr. 66 314-8 (2010)
PMID: 20179344

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-126227 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Huntingtin-interacting protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 120 amino acids
Theoretical weight: 14.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00291 (Residues: 361-480; Coverage: 12%)
Gene name: HIP1
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 35.801Å b: 57.092Å c: 81.161Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.235 0.28
Expression system: Escherichia coli