Function and Biology Details
Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116387 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (3 distinct):
DNA-(apurinic or apyrimidinic site) lyase
Molecule details ›
Chain: A
Length: 290 amino acids
Theoretical weight: 34.22 KDa
Source organism: Clostridium acetobutylicum
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 290 amino acids
Theoretical weight: 34.22 KDa
Source organism: Clostridium acetobutylicum
Expression system: Escherichia coli
UniProt:
- Canonical:
Q97FM4 (Residues: 1-290; Coverage: 99%)
Sequence domains:
- 8-oxoguanine DNA glycosylase, N-terminal domain
- HhH-GPD superfamily base excision DNA repair protein
