› 3i35

X-ray diffraction
1.4Å resolution

Human SH3 domain of protein LASP1

Released:
DOI: 10.2210/pdb3i35/pdb
PDB entry 3i35 coloured by chain, front view.
PDB entry 3i35 coloured by chain, side view.
PDB entry 3i35 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Siponen MI, Roos AK, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson A, Johansson I, Karlberg T, Kotenyova T, Kotzsch A, Kragh Nielsen T, Moche M, Nyman T, Persson C, Sagemark J, Schueler H, Schutz P, Thorsell AG, Tresaugues L, Van Den Berg S, Weigelt J, Welin M, Wisniewska M, Nordlund P, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172111 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LIM and SH3 domain protein 1 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 6.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14847 (Residues: 202-261; Coverage: 23%)
Gene names: LASP1, MLN50
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P2
Unit cell:
a: 25.348Å b: 23.235Å c: 44.716Å
α: 90° β: 92.47° γ: 90°
R-values:
R R work R free
0.203 0.202 0.222
Expression system: Escherichia coli

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