› 3i84

X-ray diffraction
2Å resolution

The Crystal Structure of Human EMMPRIN N-terminal Domain 1 in P6(1)22 space group

Released:
DOI: 10.2210/pdb3i84/pdb
PDB entry 3i84 coloured by chain, front view.
PDB entry 3i84 coloured by chain, side view.
PDB entry 3i84 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the EMMPRIN N-terminal domain 1: dimerization via beta-strand swapping.
Luo J, Teplyakov A, Obmolova G, Malia T, Wu SJ, Beil E, Baker A, Swencki-Underwood B, Zhao Y, Sprenkle J, Dixon K, Sweet R, Gilliland GL
Proteins 77 1009-14 (2009)
PMID: 19768682

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-152971 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Basigin Chains: A, B
Molecule details ›
Chains: A, B
Length: 98 amino acids
Theoretical weight: 10.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P35613 (Residues: 140-219; Coverage: 22%)
Gene names: BSG, UNQ6505/PRO21383
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P6122
Unit cell:
a: 100.371Å b: 100.371Å c: 103.866Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.188 0.207
Expression system: Homo sapiens

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Citations

7 review citations

Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
Yurchenko et al. (2010)
6 more

4 mentions without citation

Human cell receptors: potential drug targets to combat COVID-19.
Raghav et al. (2021)
3 more