› 3iho

X-ray diffraction
2.7Å resolution

The C-terminal glycosylase domain of human MBD4

Released:
DOI: 10.2210/pdb3iho/pdb
PDB entry 3iho coloured by chain, front view.
PDB entry 3iho coloured by chain, side view.
PDB entry 3iho coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Amaya MF, Xu C, Bian CB, Bountra C, Weigelt J, Arrowsmith CH, Edwards AM, Bochkarev A, Min J, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131865 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Methyl-CpG-binding domain protein 4 Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 16.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95243 (Residues: 437-574; Coverage: 24%)
Gene names: MBD4, MED1
Structure domains: Hypothetical protein; domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: R3
Unit cell:
a: 83.541Å b: 83.541Å c: 73.956Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.182 0.29
Expression system: Escherichia coli

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