› 3iu0

X-ray diffraction
1.9Å resolution

Structural basis for zymogen activation and substrate binding of transglutaminase from Streptomyces mobaraense

Released:
DOI: 10.2210/pdb3iu0/pdb
PDB entry 3iu0 coloured by chain, front view.
PDB entry 3iu0 coloured by chain, side view.
PDB entry 3iu0 coloured by chain, top view.
Source organism: Streptomyces mobaraensis
Entry author: Li TT

Function and Biology Details

Reaction catalysed: 
A protein-L-glutamine + a protein-L-lysine = a protein with an N(6)-(gamma-glutamyl)-L-lysine cross-link + NH(3)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160522 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein-glutamine gamma-glutamyltransferase Chain: A
Molecule details ›
Chain: A
Length: 382 amino acids
Theoretical weight: 43.33 KDa
Source organism: Streptomyces mobaraensis
Expression system: Escherichia coli
UniProt:
  • Canonical: P81453 (Residues: 32-407; Coverage: 100%)
Sequence domains: Microbial transglutaminase
Structure domains: Protein-glutamine gamma-glutamyltransferase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P212121
Unit cell:
a: 64.333Å b: 67.123Å c: 83.969Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.21 0.244
Expression system: Escherichia coli

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